Evidence from systematic literature review

Overview of available diagnostic assays

Target	Test	Number of references	Investigated species	Reference ID
Antibody	Agar gel immunodiffusion test (AGIDT)	8	Cattle, Goat, Sheep	7689, 7714, 7726, 7960, 8211, 8254, 8364, 41619
	Complement fixation test (CFT)	1	Cattle	41619
	ELISA, Blocking ELISA (B-ELISA)	1	Cattle, Sheep	8284
	ELISA, Competitive ELISA (C-ELISA)	22	Bison, Cattle, Goat, Llama, Reindeer, Sheep, Wapiti elk	6815, 7066, 7318, 7393, 7459, 7514, 7519, 7579, 7621, 7629, 7648, 7689, 7714, 7726, 7809, 7960, 8098, 8211, 8220, 8254, 8284, 8364
	Enzyme linked immunosorbent assay (ELISA)	2	Cattle, Sheep	7459, 60600
	IgG ELISA	1	Cattle	6815
	Indirect ELISA (I-ELISA)	1	Sheep	7579
	Seroneutralisation test	5	Cattle, Goat, Sheep	7066, 7648, 7809, 7960, 8254
	Virus neutralisation test (VNT)	1	Sheep	41619
Antigen	Agar gel immunodiffusion test (AGIDT)	1	Buffalo, Camel, Cattle, Goat, Sheep	40087
	Enzyme linked immunosorbent assay (ELISA)	1	Buffalo, Camel, Cattle, Goat, Sheep	40087
Nucleic acid	Polymerase chain reaction (PCR)	1	Cattle, Sheep	60600
	Real-Time PCR (qualitative or quantitative)	2	Cattle, Sheep	7514, 7519

Diagnostic sensitivity

The figure below presents all the results from studies in which the diagnostic sensitivity was actually reported. The number of occurrences for each diagnostic test is reported in square brackets. Please note that the range of values might refer to different target species.

Diagnostic specificity

The figure below presents all the results from studies in which the diagnostic specificity was actually reported. The number of occurrences for each diagnostic test is reported in square brackets. Please note that the range of values might refer to different target species. 

Summary of available data

Below you can find a summary of the main features of each study:

• RefID: Reference ID (to be used to retrieve full reference below)
  
• Species: in which animal species the diagnostic assays have been tested
  
• Target: Antigen, Antibody, Nucleic acid or Virus
  
• Lab test: type diagnostic assays evaluated in the study
  
• Study type: Cohort, Cross-sectional, Diagnostic test validation, Longitudinal
  
• Nr tested: number of samples tested within the study. When multiple groups were tested, the range of sample sizes is reported
  
• Nr positive: number of samples that tested positive. When multiple groups were tested, the range of positive results is reported
  
• Se: whether an estimate of diagnostic test sensitivity was reported in the article
  
• Sp: whether an estimate of diagnostic test specificity was reported in the article
   

REFERENCES

In the left panel you can find information about the entire systematic literature review. The specific references for this agent, and used in this section of the disease profiles are listed below.