The table below presents all the results from studies in which the performance of a test (the “index test”) was reported. In these cases, it is assumed that sensitivity and specificity were calculated based on a known infectious status of the animal. The numbers reported are the sensitivity and specificity directly reported by authors. Sensitivity and specificity have been calculated during data analysis only when the number of true positives and true negatives were explicitly reported. The refID can be used to consult references in the reference tables further below.
| refID | Reference | groupID | Target Species | Lab Test | Sensitivity | Specificity | Test Limit | Time Point | nTested | nTruePOS | nTrueNEG | nPOS | nNEG | Route | Dose | infMode | Context | Sampl. Strategy | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 19 | 8098 | Afshar A, et al. 1995. | 4 | Bison | ELISA, Competitive ELISA (C-ELISA) | 100 | negative samples had values of less than 50% inhibition | 323 | 23 | 300 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Objective (random) sampling | ||||
| 1 | 7318 | Niedbalski W. 2011. | 1 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 312 | 2 | 310 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 2 | 7318 | Niedbalski W. 2011. | 1 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 74 | 74 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | |||||
| 3 | 7318 | Niedbalski W. 2011. | 2 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 455 | 3 | 452 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 4 | 7318 | Niedbalski W. 2011. | 2 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 74 | 73 | 1 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 5 | 7318 | Niedbalski W. 2011. | 3 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | A sample is considered positive, if S/N percentage (ratio between the OD of analysed serum (S) and the OD of the negative (N) control) is lower or equal 70%. | 276 | 0 | 276 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 6 | 7318 | Niedbalski W. 2011. | 3 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | A sample is considered positive, if S/N percentage (ratio between the OD of analysed serum (S) and the OD of the negative (N) control) is lower or equal 70%. | 72 | 72 | 0 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 7 | 7318 | Niedbalski W. 2011. | 3 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | A sample is considered positive, if S/N percentage (ratio between the OD of analysed serum (S) and the OD of the negative (N) control) is lower or equal 70%. | 298 | 247 | 51 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 8 | 7318 | Niedbalski W. 2011. | 2 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 467 | 325 | 142 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 9 | 7318 | Niedbalski W. 2011. | 1 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | not given/not relevant | 432 | 417 | 15 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | ||||
| 10 | 7393 | Niedbalski W. 2010. | 1 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | not given/not relevant | 498 | 80 | 418 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Census | |||
| 11 | 7393 | Niedbalski W. 2010. | 2 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | not given/not relevant | 818 | 276 | 542 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Census | |||
| 12 | 7393 | Niedbalski W. 2010. | 3 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | A positive reaction is scored when the percent of OD sample/OD negative control (S/N%) is <or= 35. | 359 | 76 | 283 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Census | |||
| 13 | 7393 | Niedbalski W. 2010. | 4 | Cattle | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | A positive reaction is scored when the percent of OD sample/OD negative control (S/N%) is <or= 35. | 683 | 387 | 296 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Census | |||
| 18 | 8098 | Afshar A, et al. 1995. | 3 | Llama | ELISA, Competitive ELISA (C-ELISA) | 100 | negative samples had values of less than 50% inhibition | 398 | 0 | 398 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Objective (random) sampling | ||||
| 20 | 8098 | Afshar A, et al. 1995. | 5 | reindeer | ELISA, Competitive ELISA (C-ELISA) | 100 | negative samples had values of less than 50% inhibition | 270 | 1 | 269 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Objective (random) sampling | ||||
| 14 | 7621 | Fabienne Biteau-Coroller, et al. 2006. | 1 | Sheep | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | not given/not relevant | 113 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Convenience sampling | |||||
| 15 | 7621 | Fabienne Biteau-Coroller, et al. 2006. | 1 | Sheep | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | not given/not relevant | 14 | 76 | not given/not relevant | not given/not relevant | longitudinal | not given/not relevant | Convenience sampling | ||||
| 16 | 7621 | Fabienne Biteau-Coroller, et al. 2006. | 2 | Sheep | ELISA, Competitive ELISA (C-ELISA) | 100 | 100 | not given/not relevant | 28 | 76 | not given/not relevant | not given/not relevant | longitudinal | not given/not relevant | Convenience sampling | ||||
| 17 | 8098 | Afshar A, et al. 1995. | 2 | Wapiti elk | ELISA, Competitive ELISA (C-ELISA) | 100 | negative samples had values of less than 50% inhibition | 451 | 1 | 450 | not given/not relevant | not given/not relevant | cross sectional | not given/not relevant | Objective (random) sampling |
The table below presents all the results from studies in which the
performance of a test (the “index test”) was reported in comparison to a
gold standard or reference test. In these cases, the number of true
positive and negative animals is generally not known, but the percentage
of positive and negative animals is compared to the results of the
reference test (the reference test used is given in the table).
For a given article (unique refID and reference), the results for the
test being evaluated (the “index test” in the Intervention column) and
the reference test are given in individual rows. In the rows referring
to an index test, the reference test is specifically given in the column
“Reference Test”. In the rows referring to an evaluation test, if the
same article also provided an index test, the name of that test is given
in the “Evaluation Test” column.
| refID | Reference | Target Species | Intervention | Lab Test | Reference Test | Sensitivity | Specificity | Test Limit | Time Point | nTested | nTruePOS | nTrueNEG | nPOS | nNEG | Route | Dose | Infection Mode | Context | Samp. Strategy | Evaluation Test | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 139 | 40087 | Patel SS, et al. 2017. | Buffalo | Index test | Agar gel immunodiffusion test (AGIDT) | Enzyme linked immunosorbent assay (ELISA) | Not specified | not given/not relevant | 40 | not given/not relevant | not given/not relevant | 0 | 40 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 136 | 40087 | Patel SS, et al. 2017. | Buffalo | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | Test samples showing double or more than double OD492 of the mean negative control value are considered as positive | not given/not relevant | 40 | not given/not relevant | not given/not relevant | 0 | 40 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 138 | 40087 | Patel SS, et al. 2017. | Camel | Index test | Agar gel immunodiffusion test (AGIDT) | Enzyme linked immunosorbent assay (ELISA) | Not specified | not given/not relevant | 38 | not given/not relevant | not given/not relevant | 0 | 38 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 137 | 40087 | Patel SS, et al. 2017. | Camel | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | Test samples showing double or more than double OD492 of the mean negative control value are considered as positive | not given/not relevant | 38 | not given/not relevant | not given/not relevant | 0 | 38 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 140 | 40087 | Patel SS, et al. 2017. | Cattle | Index test | Agar gel immunodiffusion test (AGIDT) | Enzyme linked immunosorbent assay (ELISA) | Not specified | not given/not relevant | 77 | not given/not relevant | not given/not relevant | 0 | 77 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 135 | 40087 | Patel SS, et al. 2017. | Cattle | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | Test samples showing double or more than double OD492 of the mean negative control value are considered as positive | not given/not relevant | 77 | not given/not relevant | not given/not relevant | 2 | 75 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 144 | 41619 | Grimes JE, et al. 1983. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Not specified other than strong precipitin reaction for positive or weak/delayed precipitin reaction for a weak positive | not given/not relevant | 166 | not given/not relevant | not given/not relevant | 63 | 103 | not given/not relevant | not given/not relevant | Experimental infection | Diagnostic test validation | Suspect sampling | Complement fixation test (CFT) | ||
| 145 | 41619 | Grimes JE, et al. 1983. | Cattle | Index test | Complement fixation test (CFT) | Agar gel immunodiffusion test (AGIDT) | positive =titre reciprocal >20 or weak positive= titre reciprocal of 5-10. Negative= titre reciprocal <5 | not given/not relevant | 166 | not given/not relevant | not given/not relevant | 58 | 108 | not given/not relevant | not given/not relevant | Experimental infection | Diagnostic test validation | Suspect sampling | Complement fixation test (CFT) | ||
| 84 | 7726 | Velic L, et al. 2004. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 632 | not given/not relevant | not given/not relevant | 6 | 626 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 103 | 7960 | Singer RS, et al. 1998. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Soluble BTV antigen and precipitating antibodies in a positive control reagent serum diffuse through an agar gel and form a precipitin line. If the test sample contains precipitating antibodies against BTV, a line of identity will be formed that is continuous with the control precipitin line. | not given/not relevant | 24 | not given/not relevant | not given/not relevant | 21 | 3 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 105 | 8211 | Sendow I, et al. 1993. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | If the percentage inhibition of the tested serum was 40% it was considered positive | not given/not relevant | 286 | not given/not relevant | not given/not relevant | 69 | 217 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 112 | 8254 | Gustafson GA, et al. 1992. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 2206 | not given/not relevant | not given/not relevant | 1335 | 871 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 127 | 8364 | Afshar A, et al. 1989. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 540 | not given/not relevant | not given/not relevant | 300 | 240 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 129 | 8364 | Afshar A, et al. 1989. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | 99.34 | not given/not relevant | not given/not relevant | 900 | not given/not relevant | not given/not relevant | 6 | 894 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 130 | 8364 | Afshar A, et al. 1989. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | 98.25 | not given/not relevant | not given/not relevant | 400 | not given/not relevant | not given/not relevant | 7 | 393 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 132 | 8364 | Afshar A, et al. 1989. | Cattle | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | 99.00 | not given/not relevant | not given/not relevant | 1300 | not given/not relevant | not given/not relevant | 13 | 1287 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 117 | 8284 | Afshar A, et al. 1991. | Cattle | Reference test | ELISA, Blocking ELISA (B-ELISA) | not given/not relevant | not given/not relevant | 20 | 23 | not given/not relevant | not given/not relevant | 23 | 0 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 62 | 7514 | Kramps JohannesA, et al. 2008. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Real-Time PCR (qualitative or quantitative) | S/N ratios <0.4 were considered as positive. | not given/not relevant | 470 | not given/not relevant | not given/not relevant | 268 | 202 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 67 | 7519 | Frank Vandenbussche, et al. 2008. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Real-Time PCR (qualitative or quantitative) | 88.65 | 97.8 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 70 | 7629 | Cagienard A, et al. 2006. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 96.5 | The test specificity and its 95% confidence intervals (C.I. lower limit, C.I. upper limit) were calculated using Win Episcope 2 software | not given/not relevant | 2437 | not given/not relevant | not given/not relevant | 86 | 2312 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 82 | 7726 | Velic L, et al. 2004. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | 632 | not given/not relevant | not given/not relevant | 6 | 626 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 101 | 7960 | Singer RS, et al. 1998. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | Positive samples result in greater than 30% inhibition of the binding of the MAb to the BTV antigen (an optical density that is less than 70% of the negative control). | not given/not relevant | 26 | not given/not relevant | not given/not relevant | 25 | 1 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 104 | 8211 | Sendow I, et al. 1993. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | If the percentage inhibition of the tested serum was 40% it was considered positive | not given/not relevant | 286 | not given/not relevant | not given/not relevant | 111 | 175 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 106 | 8220 | Afshar A, et al. 1992. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 95.2 | 100 | samples that inhibited > or = 50% of MAb activity were considered positive relative to the MAb 3-17-43 | not given/not relevant | 462 | not given/not relevant | not given/not relevant | 191 | 271 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 107 | 8220 | Afshar A, et al. 1992. | Cattle | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | samples that inhibited > or = 50% of MAb activity were considered positive | not given/not relevant | 462 | not given/not relevant | not given/not relevant | 201 | 261 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 108 | 8220 | Afshar A, et al. 1992. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 96.9 | 95.8 | samples that inhibited > or = 50% of MAb activity were considered positive | not given/not relevant | 462 | not given/not relevant | not given/not relevant | 204 | 258 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) |
| 113 | 8254 | Gustafson GA, et al. 1992. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | Samples were positive if there was 40% or greater inhibition of the MAb | not given/not relevant | 1882 | not given/not relevant | not given/not relevant | 689 | 1193 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 115 | 8254 | Gustafson GA, et al. 1992. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | Samples were positive if there was 40% or greater inhibition of the MAb | not given/not relevant | 2206 | not given/not relevant | not given/not relevant | 725 | 1481 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 116 | 8284 | Afshar A, et al. 1991. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Blocking ELISA (B-ELISA) | not given/not relevant | 10 | 23 | not given/not relevant | not given/not relevant | 22 | 1 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 119 | 8284 | Afshar A, et al. 1991. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Blocking ELISA (B-ELISA) | not given/not relevant | 20 | 23 | not given/not relevant | not given/not relevant | 23 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 120 | 8364 | Afshar A, et al. 1989. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 100 | if they inhibited >50% of the Mab activity in the competitive Elisa | not given/not relevant | 900 | not given/not relevant | not given/not relevant | 0 | 900 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 121 | 8364 | Afshar A, et al. 1989. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 99.75 | if they inhibited >50% of the Mab activity in the competitive Elisa | not given/not relevant | 400 | not given/not relevant | not given/not relevant | 1 | 399 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 124 | 8364 | Afshar A, et al. 1989. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 99.92 | if they inhibited >50% of the Mab activity in the competitive Elisa | not given/not relevant | 1300 | not given/not relevant | not given/not relevant | 1 | 1299 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 125 | 8364 | Afshar A, et al. 1989. | Cattle | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | Samples were considered positive if they inhibited 50% or more of the MAb activity. | not given/not relevant | 540 | not given/not relevant | not given/not relevant | 259 | 281 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 65 | 7519 | Frank Vandenbussche, et al. 2008. | Cattle | Reference test | Real-Time PCR (qualitative or quantitative) | not given/not relevant | 99.5 | 98.47 | cut off was set at Ct-value of 40 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 102 | 7960 | Singer RS, et al. 1998. | Cattle | Reference test | Seroneutralisation test | not given/not relevant | considered to be positive for BTV if it had a titer 20 to any one of the 5 serotypes tested. Due to the potential for cross-reactions among BTV serotypes (Thomas, 1985; Rossitto and MacLachlan, 1992), a titer 40 to any serotype was considered to be indicative of exposure to that specific serotype. | not given/not relevant | 26 | not given/not relevant | not given/not relevant | 25 | 1 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 114 | 8254 | Gustafson GA, et al. 1992. | Cattle | Reference test | Seroneutralisation test | not given/not relevant | Sera was considered positive if a 75% reduction of CPE was observed | not given/not relevant | 1882 | not given/not relevant | not given/not relevant | 724 | 1158 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 1 | 6815 | Jean-Baptiste Hanon, et al. 2016. | Cattle | Index test | IgG ELISA | ELISA, Competitive ELISA (C-ELISA) | Negative if only the blue control line is visible, positive if blue control and red test line are visible | not given/not relevant | 138 | not given/not relevant | not given/not relevant | 105 | 33 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Other | IgG ELISA | ||
| 3 | 6815 | Jean-Baptiste Hanon, et al. 2016. | Cattle | Index test | IgG ELISA | ELISA, Competitive ELISA (C-ELISA) | Negative if only the blue control line is visible, positive if blue control and red test line are visible | not given/not relevant | 138 | not given/not relevant | not given/not relevant | 105 | 33 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Other | IgG ELISA | ||
| 148 | 60600 | van Rijn, et al. 2012. | Cattle | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 2360 | not given/not relevant | not given/not relevant | 403 | 1957 | not given/not relevant | not given/not relevant | Natural infection | Diagnostic test validation | Census | Polymerase chain reaction (PCR) | ||
| 149 | 60600 | van Rijn, et al. 2012. | Cattle | Index test | Polymerase chain reaction (PCR) | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | not given/not relevant | 2360 | not given/not relevant | not given/not relevant | 399 | 1981 | not given/not relevant | not given/not relevant | Natural infection | Diagnostic test validation | Census | Polymerase chain reaction (PCR) | ||
| 2 | 6815 | Jean-Baptiste Hanon, et al. 2016. | Cattle | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 138 | not given/not relevant | not given/not relevant | 93 | 45 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Other | not given/not relevant | ||
| 71 | 7629 | Cagienard A, et al. 2006. | Cattle | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 158 | not given/not relevant | not given/not relevant | 0 | 158 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | not given/not relevant | ||
| 63 | 7514 | Kramps JohannesA, et al. 2008. | Cattle | Reference test | Real-Time PCR (qualitative or quantitative) | not given/not relevant | not given/not relevant | not given/not relevant | 470 | not given/not relevant | not given/not relevant | 267 | 203 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Selective (risk-based) sampling | not given/not relevant | ||
| 141 | 40087 | Patel SS, et al. 2017. | Goat | Index test | Agar gel immunodiffusion test (AGIDT) | Enzyme linked immunosorbent assay (ELISA) | Not specified | not given/not relevant | 70 | not given/not relevant | not given/not relevant | 11 | 59 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 134 | 40087 | Patel SS, et al. 2017. | Goat | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | Test samples showing double or more than double OD492 of the mean negative control value are considered as positive | not given/not relevant | 70 | not given/not relevant | not given/not relevant | 40 | 30 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 81 | 7714 | Prabhakar TG, et al. 2005. | Goat | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 165 | not given/not relevant | not given/not relevant | 62 | 103 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 133 | 8364 | Afshar A, et al. 1989. | Goat | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | 99.38 | Standard method of Pearson and Jochim 1979 | not given/not relevant | 160 | not given/not relevant | not given/not relevant | 1 | 159 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 73 | 7648 | Oya Bulut, et al. 2006. | Goat | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | 100 | 96 | not given/not relevant | not given/not relevant | 181 | not given/not relevant | not given/not relevant | 109 | 72 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 79 | 7714 | Prabhakar TG, et al. 2005. | Goat | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 85.5 | 88.3 | not given/not relevant | not given/not relevant | 165 | not given/not relevant | not given/not relevant | 141 | 24 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 123 | 8364 | Afshar A, et al. 1989. | Goat | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 100 | if they inhibited >50% of the Mab activity in the competitive Elisa | not given/not relevant | 160 | not given/not relevant | not given/not relevant | 0 | 160 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 75 | 7648 | Oya Bulut, et al. 2006. | Goat | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | not given/not relevant | 181 | not given/not relevant | not given/not relevant | 97 | 84 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 142 | 40087 | Patel SS, et al. 2017. | Sheep | Index test | Agar gel immunodiffusion test (AGIDT) | Enzyme linked immunosorbent assay (ELISA) | Not specified | not given/not relevant | 139 | not given/not relevant | not given/not relevant | 17 | 122 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 143 | 40087 | Patel SS, et al. 2017. | Sheep | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | Test samples showing double or more than double OD492 of the mean negative control value are considered as positive | not given/not relevant | 139 | not given/not relevant | not given/not relevant | 67 | 72 | not given/not relevant | not given/not relevant | Natural infection | cross sectional | Unspecified | Agar gel immunodiffusion test (AGIDT) | ||
| 77 | 7689 | Smriti Shringi, et al. 2005. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 178 | not given/not relevant | not given/not relevant | 17 | 161 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 80 | 7714 | Prabhakar TG, et al. 2005. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 300 | not given/not relevant | not given/not relevant | 104 | 196 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 85 | 7726 | Velic L, et al. 2004. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 8967 | not given/not relevant | not given/not relevant | 141 | 8826 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 97 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Soluble BTV antigen and precipitating antibodies in a positive control reagent serum diffuse through an agar gel and form a precipitin line. If the test sample contains precipitating antibodies against BTV, a line of identity will be formed that is continuous with the control precipitin line. | not given/not relevant | 9 | not given/not relevant | not given/not relevant | 5 | 4 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 98 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Soluble BTV antigen and precipitating antibodies in a positive control reagent serum diffuse through an agar gel and form a precipitin line. If the test sample contains precipitating antibodies against BTV, a line of identity will be formed that is continuous with the control precipitin line. | not given/not relevant | 22 | not given/not relevant | not given/not relevant | 22 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 99 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Soluble BTV antigen and precipitating antibodies in a positive control reagent serum diffuse through an agar gel and form a precipitin line. If the test sample contains precipitating antibodies against BTV, a line of identity will be formed that is continuous with the control precipitin line. | not given/not relevant | 20 | not given/not relevant | not given/not relevant | 20 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 100 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Soluble BTV antigen and precipitating antibodies in a positive control reagent serum diffuse through an agar gel and form a precipitin line. If the test sample contains precipitating antibodies against BTV, a line of identity will be formed that is continuous with the control precipitin line. | not given/not relevant | 39 | not given/not relevant | not given/not relevant | 26 | 13 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 128 | 8364 | Afshar A, et al. 1989. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | not given/not relevant | 65 | not given/not relevant | not given/not relevant | 42 | 23 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 131 | 8364 | Afshar A, et al. 1989. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | 99.44 | not given/not relevant | not given/not relevant | 530 | not given/not relevant | not given/not relevant | 3 | 527 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 118 | 8284 | Afshar A, et al. 1991. | Sheep | Reference test | ELISA, Blocking ELISA (B-ELISA) | not given/not relevant | not given/not relevant | 10 | 23 | not given/not relevant | not given/not relevant | 21 | 2 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Unspecified | ELISA, Competitive ELISA (C-ELISA) | ||
| 4 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 5 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 6 | 27 | not given/not relevant | not given/not relevant | 1 | 26 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 6 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 7 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 6 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 8 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 9 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 6 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 10 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 6 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 11 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 6 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 12 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 7 | 27 | not given/not relevant | not given/not relevant | 7 | 20 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 13 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 8 | 12 | not given/not relevant | not given/not relevant | 10 | 2 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 14 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 9 | 12 | not given/not relevant | not given/not relevant | 10 | 2 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 15 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 10 | 27 | not given/not relevant | not given/not relevant | 24 | 3 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 16 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 11 | 10 | not given/not relevant | not given/not relevant | 10 | not given/not relevant | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 17 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 18 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 7 | 27 | not given/not relevant | not given/not relevant | 3 | 24 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 19 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 8 | 12 | not given/not relevant | not given/not relevant | 9 | 3 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 20 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 9 | 12 | not given/not relevant | not given/not relevant | 12 | not given/not relevant | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 21 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 11 | 10 | not given/not relevant | not given/not relevant | 10 | 10 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 22 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 10 | 27 | not given/not relevant | not given/not relevant | 25 | 2 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 23 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 7 | 27 | not given/not relevant | not given/not relevant | 3 | 24 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 24 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 8 | 12 | not given/not relevant | not given/not relevant | 2 | 10 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 25 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 9 | 12 | not given/not relevant | not given/not relevant | 10 | 2 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 26 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 10 | 27 | not given/not relevant | not given/not relevant | 24 | 3 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 27 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 11 | 10 | not given/not relevant | not given/not relevant | 10 | 0 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 28 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 7 | 27 | not given/not relevant | not given/not relevant | 4 | 23 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 29 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 8 | 12 | not given/not relevant | not given/not relevant | 8 | 4 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 30 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 9 | 12 | not given/not relevant | not given/not relevant | 12 | 0 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 31 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 10 | 27 | not given/not relevant | not given/not relevant | 26 | 1 | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 32 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 11 | 10 | not given/not relevant | not given/not relevant | 10 | not given/not relevant | not given/not relevant | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 33 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 34 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 7 | 27 | not given/not relevant | not given/not relevant | 10 | 17 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 35 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 8 | 12 | not given/not relevant | not given/not relevant | 12 | 0 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 36 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 9 | 12 | not given/not relevant | not given/not relevant | 12 | 0 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 37 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 10 | 27 | not given/not relevant | not given/not relevant | 27 | 0 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 38 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | 11 | 27 | not given/not relevant | not given/not relevant | 27 | 0 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 54 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | not given/not relevant | not given/not relevant | 173 | not given/not relevant | not given/not relevant | 113 | 60 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 66 | 7519 | Frank Vandenbussche, et al. 2008. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Real-Time PCR (qualitative or quantitative) | 85.05 | 98.46 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 72 | 7648 | Oya Bulut, et al. 2006. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | 100 | 96 | not given/not relevant | not given/not relevant | 381 | not given/not relevant | not given/not relevant | 55 | 326 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 76 | 7689 | Smriti Shringi, et al. 2005. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 100 | 77 | not given/not relevant | not given/not relevant | 178 | not given/not relevant | not given/not relevant | 54 | 124 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 78 | 7714 | Prabhakar TG, et al. 2005. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 88.5 | 91.8 | not given/not relevant | not given/not relevant | 300 | not given/not relevant | not given/not relevant | 261 | 39 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 83 | 7726 | Velic L, et al. 2004. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | not given/not relevant | 8967 | not given/not relevant | not given/not relevant | 187 | 8780 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 86 | 7809 | Lelli R, et al. 2003. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | 100 | 99.1 | not given/not relevant | not given/not relevant | 894 | not given/not relevant | not given/not relevant | 338 | 556 | naturally infected | not given/not relevant | not given/not relevant | Diagnostic test validation | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 87 | 7809 | Lelli R, et al. 2003. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | 99.1 | 100 | not given/not relevant | not given/not relevant | 894 | not given/not relevant | not given/not relevant | 330 | 564 | naturally infected | not given/not relevant | not given/not relevant | Diagnostic test validation | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) |
| 89 | 7960 | Singer RS, et al. 1998. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | Positive samples result in greater than 30% inhibition of the binding of the MAb to the BTV antigen (an optical density that is less than 70% of the negative control). | not given/not relevant | 9 | not given/not relevant | not given/not relevant | 4 | 5 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 90 | 7960 | Singer RS, et al. 1998. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | Positive samples result in greater than 30% inhibition of the binding of the MAb to the BTV antigen (an optical density that is less than 70% of the negative control). | not given/not relevant | 22 | not given/not relevant | not given/not relevant | 22 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 91 | 7960 | Singer RS, et al. 1998. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | Positive samples result in greater than 30% inhibition of the binding of the MAb to the BTV antigen (an optical density that is less than 70% of the negative control). | not given/not relevant | 39 | not given/not relevant | not given/not relevant | 28 | 11 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 92 | 7960 | Singer RS, et al. 1998. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Seroneutralisation test | Positive samples result in greater than 30% inhibition of the binding of the MAb to the BTV antigen (an optical density that is less than 70% of the negative control). | not given/not relevant | 20 | not given/not relevant | not given/not relevant | 20 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 109 | 8220 | Afshar A, et al. 1992. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 96.9 | 100 | samples that inhibited > or = 50% of MAb activity were considered positive | not given/not relevant | 156 | not given/not relevant | not given/not relevant | 28 | 128 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 110 | 8220 | Afshar A, et al. 1992. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 95.2 | 100 | samples that inhibited > or = 50% of MAb activity were considered positive relative to the MAb 3-17-43 | not given/not relevant | 156 | not given/not relevant | not given/not relevant | 29 | 126 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 111 | 8220 | Afshar A, et al. 1992. | Sheep | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | samples that inhibited > or = 50% of MAb activity were considered positive | not given/not relevant | 156 | not given/not relevant | not given/not relevant | 30 | 126 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 122 | 8364 | Afshar A, et al. 1989. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | 99.63 | if they inhibited >50% of the Mab activity in the competitive Elisa | not given/not relevant | 530 | not given/not relevant | not given/not relevant | 2 | 528 | not given/not relevant | not given/not relevant | not given/not relevant | cohort | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | |
| 126 | 8364 | Afshar A, et al. 1989. | Sheep | Index test | ELISA, Competitive ELISA (C-ELISA) | Agar gel immunodiffusion test (AGIDT) | Samples were considered positive if they inhibited 50% or more of the MAb activity. | not given/not relevant | 65 | not given/not relevant | not given/not relevant | 43 | 22 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Convenience sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 64 | 7519 | Frank Vandenbussche, et al. 2008. | Sheep | Reference test | Real-Time PCR (qualitative or quantitative) | not given/not relevant | 99.55 | 98.48 | cut-off was set at a Ct-value of 40 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Suspect sampling | ELISA, Competitive ELISA (C-ELISA) |
| 53 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | not given/not relevant | 173 | not given/not relevant | not given/not relevant | 79 | 94 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | ELISA, Competitive ELISA (C-ELISA) | ||
| 74 | 7648 | Oya Bulut, et al. 2006. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | not given/not relevant | 381 | not given/not relevant | not given/not relevant | 53 | 328 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 93 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | considered to be positive for BTV if it had a titer 20 to any one of the 5 serotypes tested. Due to the potential for cross-reactions among BTV serotypes (Thomas, 1985; Rossitto and MacLachlan, 1992), a titer 40 to any serotype was considered to be indicative of exposure to that specific serotype. | not given/not relevant | 9 | not given/not relevant | not given/not relevant | 4 | 5 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 94 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | considered to be positive for BTV if it had a titer 20 to any one of the 5 serotypes tested. Due to the potential for cross-reactions among BTV serotypes (Thomas, 1985; Rossitto and MacLachlan, 1992), a titer 40 to any serotype was considered to be indicative of exposure to that specific serotype. | not given/not relevant | 22 | not given/not relevant | not given/not relevant | 20 | 2 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 95 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | considered to be positive for BTV if it had a titer 20 to any one of the 5 serotypes tested. Due to the potential for cross-reactions among BTV serotypes (Thomas, 1985; Rossitto and MacLachlan, 1992), a titer 40 to any serotype was considered to be indicative of exposure to that specific serotype. | not given/not relevant | 20 | not given/not relevant | not given/not relevant | 18 | 2 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 96 | 7960 | Singer RS, et al. 1998. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | considered to be positive for BTV if it had a titer 20 to any one of the 5 serotypes tested. Due to the potential for cross-reactions among BTV serotypes (Thomas, 1985; Rossitto and MacLachlan, 1992), a titer 40 to any serotype was considered to be indicative of exposure to that specific serotype. | not given/not relevant | 39 | not given/not relevant | not given/not relevant | 25 | 14 | not given/not relevant | not given/not relevant | not given/not relevant | longitudinal | Selective (risk-based) sampling | ELISA, Competitive ELISA (C-ELISA) | ||
| 58 | 7459 | Pourquier P, et al. 2009. | Sheep | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | 6 | 6 | not given/not relevant | not given/not relevant | 0 | 6 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 59 | 7459 | Pourquier P, et al. 2009. | Sheep | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 302 | not given/not relevant | not given/not relevant | 0 | 302 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 61 | 7459 | Pourquier P, et al. 2009. | Sheep | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 154 | not given/not relevant | not given/not relevant | 154 | 0 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 56 | 7459 | Pourquier P, et al. 2009. | Sheep | Index test | Enzyme linked immunosorbent assay (ELISA) | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | 6 | 6 | not given/not relevant | not given/not relevant | 6 | not given/not relevant | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 57 | 7459 | Pourquier P, et al. 2009. | Sheep | Index test | Enzyme linked immunosorbent assay (ELISA) | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | 302 | not given/not relevant | not given/not relevant | 0 | 302 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 60 | 7459 | Pourquier P, et al. 2009. | Sheep | Index test | Enzyme linked immunosorbent assay (ELISA) | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | not given/not relevant | 154 | not given/not relevant | not given/not relevant | 154 | 0 | not given/not relevant | not given/not relevant | not given/not relevant | Diagnostic test validation | Census | Enzyme linked immunosorbent assay (ELISA) | ||
| 68 | 7579 | Bhanuprakash V, et al. 2007. | Sheep | Reference test | ELISA, Competitive ELISA (C-ELISA) | not given/not relevant | 83.83 | 85.95 | not given/not relevant | not given/not relevant | 788 | not given/not relevant | not given/not relevant | 417 | 371 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | Indirect ELISA (I-ELISA) |
| 69 | 7579 | Bhanuprakash V, et al. 2007. | Sheep | Index test | Indirect ELISA (I-ELISA) | ELISA, Competitive ELISA (C-ELISA) | 88.25 | 80.86 | Cut off value was 0.18 at OD 492 (2X mean OD of standard negative sera in each plate) | not given/not relevant | 788 | not given/not relevant | not given/not relevant | 439 | 349 | not given/not relevant | not given/not relevant | not given/not relevant | cross sectional | Objective (random) sampling | Indirect ELISA (I-ELISA) |
| 150 | 60600 | van Rijn, et al. 2012. | Sheep | Reference test | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | not given/not relevant | not given/not relevant | 225 | not given/not relevant | not given/not relevant | 230 | 221 | not given/not relevant | not given/not relevant | Natural infection | Diagnostic test validation | Census | Polymerase chain reaction (PCR) | ||
| 151 | 60600 | van Rijn, et al. 2012. | Sheep | Index test | Polymerase chain reaction (PCR) | Enzyme linked immunosorbent assay (ELISA) | not given/not relevant | not given/not relevant | 225 | not given/not relevant | not given/not relevant | 247 | 194 | not given/not relevant | not given/not relevant | Natural infection | Diagnostic test validation | Census | Polymerase chain reaction (PCR) | ||
| 39 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 5 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 40 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 6 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 41 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 7 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 42 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 5 | 27 | not given/not relevant | not given/not relevant | 0 | 27 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 43 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 9 | 9 | not given/not relevant | not given/not relevant | 3 | 6 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 44 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 10 | 15 | not given/not relevant | not given/not relevant | 9 | 6 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 45 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 11 | 7 | not given/not relevant | not given/not relevant | 7 | 0 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 46 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | 5 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 47 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | 6 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 48 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | 7 | 15 | not given/not relevant | not given/not relevant | 0 | 15 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 49 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | 8 | 9 | not given/not relevant | not given/not relevant | 2 | 7 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 50 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 9 | 9 | not given/not relevant | not given/not relevant | 2 | 7 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 51 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | 10 | 15 | not given/not relevant | not given/not relevant | 2 | 13 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 52 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | not given/not relevant | 11 | 8 | not given/not relevant | not given/not relevant | 3 | 5 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 55 | 7066 | Gabriella Worwa, et al. 2013. | Sheep | Index test | Seroneutralisation test | Seroneutralisation test | not given/not relevant | not given/not relevant | 173 | not given/not relevant | not given/not relevant | 97 | 76 | subcutaneous | 2.1 ml 1:2 BTV-8 infected cattle blood | not given/not relevant | longitudinal | Census | Seroneutralisation test | ||
| 146 | 41619 | Grimes JE, et al. 1983. | Sheep | Reference test | Agar gel immunodiffusion test (AGIDT) | not given/not relevant | Positive denotes strong precipitin line; weak positive denotes a weak or delayed precipitin reaction; negative denotes no visible precipitin reaction | not given/not relevant | 98 | not given/not relevant | not given/not relevant | 59 | 39 | not given/not relevant | not given/not relevant | Experimental infection | Diagnostic test validation | Convenience sampling | Virus neutralisation test (VNT) | ||
| 147 | 41619 | Grimes JE, et al. 1983. | Sheep | Index test | Virus neutralisation test (VNT) | Agar gel immunodiffusion test (AGIDT) | 1-9 = negative, > or=50 = positive | not given/not relevant | 98 | not given/not relevant | not given/not relevant | 37 | 49 | not given/not relevant | not given/not relevant | Experimental infection | Diagnostic test validation | Convenience sampling | Virus neutralisation test (VNT) | ||
| 88 | 7809 | Lelli R, et al. 2003. | Sheep | Reference test | Seroneutralisation test | not given/not relevant | 100 | 100 | not given/not relevant | not given/not relevant | 894 | not given/not relevant | not given/not relevant | 333 | 561 | naturally infected | not given/not relevant | not given/not relevant | Diagnostic test validation | Objective (random) sampling | not given/not relevant |
In the left panel you can find information about the entire systematic literature review. The specific references for this agent, and used in this section of the story map are listed below.